Sclerosing adenosis (SA) is a benign proliferative condition of the terminal duct lobular units characterised by an increased number of acini and their glands. English Translation, Synonyms, Definitions and Usage Examples of Spanish Word ‘adenosis esclerosante mamaria’. el diagnóstico diferencial de lesiones benignas que simulan carcinoma, tales como hiperplasia cribiforme, adenosis esclerosante e hiperplasia adenomatosa .

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The pathogenesis of SPA is unknown, although there has been a possible association with the Epstein-Barr virus 7 and in this particular case there is a history of chronic infection with this virus.

The treatment in most cases consists of excision of the tumor with escldrosante superficial parotidectomy with adequate surgical margins and facial nerve sparing, which has demonstrated a prolonged survival.

Sclerosing adenosis can appear as a focal or diffuse lesion. Multinodular, cuts with increased resistance Gritty but no chalky yellow white foci or streaks. Microscopically the SPA consists of lobes circumscribed by hyaline connective tissue. Synonyms or Alternate Spellings: There is no gender predominance, although it is considered a slight predilection toward females.

It is important to carry out the differential diagnosis with other salivary gland tumours, mainly aednosis cell carcinoma.

What does sclerosing adenosis mean? Definition, meaning and sense

Hay pruebas de que existen poblaciones celulares monoclonales. The normal lobular architecture of the breast is maintained, but becomes exaggerated and distorted. The treatment consists in excision of the tumor with a superficial parotidectomy, which has demonstrated high cure rates. A superficial parotidectomy was done and the microscopic study informed SPA. The lymph nodes were negative for malignancy. SPA is considered a disease due aenosis a pseudotumoral inflammatory reaction.


Most cases appear in the major salivary glands, especially in the parotid gland. We report a case of sclerosing polycystic adenosis within the submandibular gland in a year-old woman. Click here for information on linking to our website or using our content or images.

adenosia Unable to process the form. Head Neck Pathol, 3pp. A total of 51 cases have been described in the literature. This is suggestive of sclerosing polycystic adenosis SPA of the parotid gland. Fibroscopy was normal, whilst bimanual and cervical palpation noticed an enlarged, left submandibular gland, with a posterior adenopathy to a mobile and rolling gland of about 2 esclrrosante in diameter.

Studies suggests that women with sclerosing adenosis may have approximately 1.

Adenosis of the Breast

To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. Sclerosing polycystic adenosis SPA is a rare, newly reported lesion of the salivary glands.

Initially, it was asymptomatic and subsequently the patient developed light dysesthesias in the region. The patient was a smoker. Specific immunohistochemistry antibodies as anti-smooth muscle actin, can confirm the integrity of the myoepithelial cells layer in benign tumors, which is lost in carcinomatous lesions.

The pathological anatomy reveals circumscribed, adebosis not encapsulated nodules, with dilated ducts and epithelial hyperplasia, surrounded by a very fibrous stroma and with chronic inflammation. A cervical computed tomography CT scan revealed a solid nodule of 16 escleroaante in the left submandibular gland, with an adenopathy of 6 mm adjacent to the submaxillary gland.

Figure 2 – The microscopic study reveal a parotid gland tissue with periductal inflammation and fibrosis with intraluminal cellular debris and polymorphic nuclear cells. Its anatomopathological appearance is similar to that of fibrocystic breast axenosis. What’s new in the AFIP fascicle on salivary gland tumors: Sclerosing adenosis Sclerosing adenosis of breast Mammary sclerosing adenosis.


Discussion There adebosis been about 51 cases of sclerosing polycyst adenosis SPA in the salivary glands published. Fig, All cases of SPA have been unilateral like this case report. Examination revealed a normal oropharynx, with reddening of the drainage orifice of the left Wharton duct. The provisional probable diagnosis was a parotid tumor with a clinical and radiological benign esclerosajte, likely a pleomorphic adenoma.

Se continuar a navegar, consideramos que aceita o seu uso. Braz J Otorhinolaryngol, 76pp. Multiple types of adenosis are described: The Journal publishes Original Articles articles on escllerosante research and clinical investigationreviews, brief communications, case studies and images, which are subjected to a rigorous peer review process.

Ultrasound-guided fine needle aspiration reported a well-differentiated acinar cell carcinoma low grade. With some types sclerosing adenosisthe risk of subsequent breast cancer is 1. Protection of human and animal subjects. Sign up for our Email Newsletters.

Rare; sclerosing adenosis with predominance of myoepithelial cells, presents as multifocal microscopic adenodis Am J Surg Pathol ; Late stage; fibrosis and decreasing acini.

Clinical presentation Many women with sclerosing adenosis experience recurring pain that tends to be linked to the menstrual cycle. Sclerosing adenosis at core biopsy in a 40 year old pregnant woman. Epithelial and myoepithelial cells. Conflict of fsclerosante The authors declare no conflict of interest. Jaya Ruth Asirvatham, M.

Accessed December 31st, SRJ is a prestige metric based on the idea that not all citations are the same.